A Protocol to Wean From Noninvasive Mechanical Ventilation

Duan jun80 enrolled

Overview

The investigators use a protocol to wean from noninvasive mechanical ventilation.

Design: Prospective, randomized, controlled trial, with 2 groups: study (protocol weaning group) and control (clinicians' order weaning group). Setting: Respiratory Intensive Care Unit (RICU). Subjects: Patients \>18 yr, noninvasive mechanical ventilation \>24 hours. Interventions and measurements: Study group (weaning as the protocol) and control group (weaning as the clinicians' order); recording of clinical variables at admission and during RICU stay, and end-point variables (noninvasive mechanical ventilation day, RICU and hospital stay, RICU mortality. Expected results: the protocol group's noninvasive mechanical ventilation days is less than clinicians' order group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

NONE

Enrollment

Conditions

Ventilator Weaning

Interventions

protocolDEVICE

In this group, the patients were weaned as the protocol.

physician's ordersOTHER

In this group, the patients were weaned as the clinicians' order.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. noninvasive mechanical ventilation \> 24 hours. 2. age \>18 years Exclusion Criteria: 1. severe cerebraI，heart，hepatic and renal faiIure. 2. facial or cranial trauma or surgery. 3. facial abnormalities. 4. recent gastric or esophageal surgery. 5. active upper gastrointestinal bleeding. 6. large amount of sputum with weak cough ability 7. lack of co-operation.

Locations (1)

The first affiated hospital, chongqing medical university

Chongqing, Chongqing Municipality, China

Outcomes

Primary Outcomes

The duration of noninvasive mechanical ventilation

The duration of noninvasive mechanical ventilation was measured from the patients admitted to ICU to discharged from it,an expected average of 4 weeks.