Early Versus Late Parenteral Nutrition in the Pediatric Intensive Care Unit

Inclusion Criteria: * All patients admitted to the PICU with a STRONGkids score of 2 points or more upon ICU admission Exclusion Criteria: * Age of 17 years or older * Patients with a DNR code at the time of ICU admission. * Patients expected to die within 12 hours (=moribund patients). * Patient readmitted to ICU after randomization to the PEPaNIC trial, more than 48 hours after the initial discharge * Patients transferred from another paediatric intensive care after a stay of more than 7 days * Patients suffering from ketoacidotic or hyperosmolar coma on admission. * Patients suffering from Short Bowel Syndrome on home PN or other conditions that require home PN * Patients suspicious or established inborn metabolic diseases requiring specific diet * STRONGkids score lower than 2 on ICU admission. * Premature Newborns ( 37 weeks gestational age upon admission in the PICU) * Prior inclusion in another randomized controlled outcome study