Role of the Stress in the Development of the Metabolic Syndrome

Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina738 enrolled

Overview

The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care. Evaluating the association between anxiety, depression, quality of life and the vital stressful events, and the development of the metabolic syndrome in general population. Our hypothesis is that population of the cohort with bigger degree of stress will develop earlier the metabolic syndrome. If our hypothesis about the metabolic syndrome are demonstrated, it would allow establishing in a future interventions on these factors of risk to prevent or to decrease the incidence of this syndrome in the Primary Care.

Study Type

OBSERVATIONAL

Enrollment

738

Conditions

Anxiety Disorders Depressive Disorders Metabolic Syndrome Stress Disorders

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Both genders, elderly than 40 years * Subjects with 1 or 2 criteria of NCEP-ATPIII set for Metabolic Syndrome * Abdominal waist \> 102 cm ( men ) or \>88 cm ( women ) * Blood Pressure ( \>130/85 mmHg ) ( or else pharmacologic treatment of hypertension ) * Hypertriglyceridaemia ( \>150 mg/dl ) ( or else pharmacologic treatment ) * HDL-cholesterol \<40 mg/dl ( men ) or \<50 mg/dl ( women ) ( or else treatment ) * Fasting glucose \> 110 mg/dl. Exclusion Criteria: * Metabolic Syndrome (NCEP-ATPIII defined)(3 criteria of above mentioned) * Severe or terminal disease * Severe mental disease that difficulties the follow-up

Outcomes

Primary Outcomes

Incidence of metabolic syndrome

Determining the incidence of metabolic syndrome ( MetS ) in people of high risk, older than 40 years and attended in the Primary Care.

Time frame: One year

Secondary Outcomes

Association between risk factors and metabolic syndrome

Association between anxiety, the depression, the quality of life and the vital stressful events and the metabolic syndrome