Mean Platelet Volume and TXA2 Levels in Patients With Polycystic Ovary Syndrome (PCOS)

AGUNCO Obstetrics and Gynecology Centre

Overview

Polycystic ovary syndrome (PCOS)is closely associated with insulin resistance and hyperinsulinemia as well as with increased incidence in diabetes, hypertension, dyslipidemia and atherosclerosis. Indeed, subjects with PCOS were reported to carry an increased long-term cardiovascular risk, among others. Aiming to correlate the mean platelet volume, the thromboxane A2 level and the PCOS, an observational study was planned. Clinical evaluation of metabolic outcomes in PCOS patients is compared to a placebo group.

Study Type

OBSERVATIONAL

Conditions

Polycystic Ovary Syndrome

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women fulfilled two out of three diagnostic criteria for PCOS Exclusion Criteria: * Pre-existing secondary endocrine disorders * History of hypertension, diabetes mellitus or cardiovascular disorders * Pharmacologic treatment in the last 6 months before entering the study.

Locations (1)

Istituto di Patologia Ostetrica e Ginecologica

Catania, Italy

Outcomes

Primary Outcomes

Mean platelet volume

Thromboxane A2

Data from ClinicalTrials.gov

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