Comparison of Three Different No-contact Pachymetries

University of Catanzaro150 enrolled

Overview

Study wants to compare central corneal thickness (CCT) obtained through 3 different no-contact instruments and to compare them with contact ultrasound pachymetry, actually the gold standard technique.

Corneal pachymetry is the measurement of corneal thickness, usually expressed in microns (μ). Pachymetry is systematically used for the monitoring of corneal oedema, for the management and assessment of the progression risk of the ocular hypertension, for the diagnosis, the management and follow-up of keratoconus, as well as it is important in the pre and postoperative management of corneal surgical procedures. CCT is a factor well known to influence tonometry. Its assessment is fundamental in glaucoma practice to allow a correct intraocular pressure (IOP) evaluation. The purpose of this study is to compare CCT measurements using four different instruments: Scheimpflug camera tomography, spectral-domain optical coherence tomography (SD-OCT), anterior chamber SD-OCT and ultrasound pachymetry.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Corneal Thickness

Interventions

PachymetryDEVICE

Healthy volunteers recruited among subject that underwent a routine ophthalmologic evaluation or among both students and workers at our clinic, will be submitted to CCT measurement through four different instruments: Scheimpflug camera tomography, SD-OCT, anterior chamber SD-OCT, and finally with US pachymeter.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * subjects that gave a valid consensus to be included in this experimentation, * aged between 18 and 75 years, * Best-Corrected Visual Acuity (BCVA) of 20/100 or better, * refraction included between -6 and +6 dioptres, * astigmatism included between -2 and +2 dioptres. Exclusion Criteria: * History of refractive surgery or any keratoplasty procedure, * corneal opacities or diseases that make not suitable applanation tonometry or pachymetry. * Use of contact lenses. * History of corneal dystrophies or degenerative diseases, (like keratoconus and pellucid marginal degeneration). * History of glaucoma or ocular hypertension.

Locations (1)

University of Catanzaro - Eye Department

Catanzaro, Italy

RECRUITING

Outcomes

Primary Outcomes

Central Corneal Thickness (CCT) expressed in microns (μm)

to valuate differences among all obtained no-contact CCT measurements and compare them with the CCT measured with the reference tool (Ultrasound pachymeter).

Time frame: partecipants will be followed for one day, i. e. until the CCT measurements with all instruments object of present study are taken

Secondary Outcomes

Central Corneal Thickness (CCT) expressed in microns (μm)

to valuate test-retest reliability of each instrument

Time frame: partecipants will be followed for one day, i. e. until the CCT measurements with all instruments object of present study are taken

Central Contacts

Luigi Varano, M. D.

CONTACT

+39 0961 3647365 luigi-varano@libero.it

Giovanni Scorcia, M. D.

CONTACT

+39 0961 3647135 scorcia@unicz.it

Data from ClinicalTrials.gov

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