The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.
Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles. The aim of this study is to examined for an association between habitual calcium intake and fecal energy and fat excretion, concentrations of substrates involved in energy metabolism, blood pressure and body weight
Study Type
OBSERVATIONAL
Enrollment
158
Dept. of Human Nutrition, Faculty of Life Sciences, University of Copenhagen
Frederiksberg, Copenhagen, Denmark
Total fat and energy excretion
Total fat and energy excretion in faeces during the test period of 5 consecutive days
Time frame: 5 days
p-vitamin D
Time frame: 1 day
p-PTH
Parathyroid hormone (PTH)
Time frame: 1 day
Selected genetic variations
DNA from blood sample
Time frame: 1 day
Blood lipids and cholesterol
Total p-cholesterol, p-LDL, p-HDL, p-TG and p-FFA
Time frame: 1 day
calcium excretion
Total calcium excretion in faeces and urin during the test period of 2 consecutive days
Time frame: 2 days
Gut micro flora
Identification of gut micro flora
Time frame: 1 day
NMR-spectroscopy based metabonomics profiling of urin
NMR-spectroscopy based metabonomics profiling of each test subject
Time frame: 1 day
blood pressure
Resting blood pressure
Time frame: 1 day
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