Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment

Yazd Medical University520 enrolled

Overview

This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia. It also compared two methods of treatment with aspirin and aspirin plus heparin.

Study Type

OBSERVATIONAL

Enrollment

520

Conditions

Recurrent Pregnancy Loss

Eligibility

Sex: FEMALEMin age: 19 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * unexplained recurrent miscarriage, * women had previous venous or arterial thromboembolism or who were heterozygous or homozygous for mutations for FV Leiden G1691A, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T) Exclusion Criteria: * abnormal karyotypes of both partners, * uterine and cervical anatomical disorders on pelvic ultrasonography or hysteroscopy, * abnormal ovaries and abnormal endocrine tests.

Locations (1)

Research and Clinical Centre for Infertility

Yazd, Yazd Province, Iran

Data from ClinicalTrials.gov

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