Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors

Korea University80 enrolled

Overview

The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Type 2 Diabetes

Interventions

Aerobic Exercise GroupBEHAVIORAL

12 weeks Aerobic exercise

Control GroupBEHAVIORAL

maintaining usual activities

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * type 2 diabetes * stable body weight * sedentary lifestyle Exclusion Criteria: * smoked cigarettes * cardiovascular disease * chronic kidney * chronic liver disease * pregnant or breastfeeding * any other major illness

Locations (1)

Eulji University School of Medicine

Seoul, South Korea

Outcomes

Primary Outcomes

change from baseline in soluble receptor for advanced glycation endproducts (sRAGE) after 12 weeks of aerobic exercise

Time frame: 12 weeks

Secondary Outcomes

anthropometric parameters

body weight, waist circumference, body fat percentage, visceral fat area

Time frame: 12 weeks

biochemical parameters

HbA1c, apolipoprotein B, free fatty acid

Time frame: 12 weeks

energy expenditure

activity energy expenditure, total energy expenditure

Time frame: 12 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.