Prevention Post Operative Nausea Vomiting in Ambulatory Gynecologic Laparoscopy

Prince of Songkla University340 enrolled

Overview

The purpose of this study is to compare the incidence of Postoperative nausea and vomiting between the intervention group who received multimodal antiemetic management and the control group who did not get this protocol.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

340

Conditions

Postoperative Nausea and Vomiting

Interventions

DexamethasoneDRUG

4 mg iv before induction for high and extremely high risk

OndansetronDRUG

4 mg iv before ended surgery 30 min

DimenhydrinateDRUG

1 mg/kg iv before ended surgery 30 min

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Ambulatory gynecologic laparoscopy * Age 18-45 years * ASA class 1-2 Exclusion Criteria: * The patients who take opioid, steroid, pyschotics or antiemetic drug within 24 hours before surgery * History of antiemetic, anesthetic and analgesic drugs allergy * Pregnancy or breast feeding * Body mass index \>34 kg/square metre

Locations (1)

Anesthesiology Department, Faculty of Medicine, Prince of Songkla University

Hat Yai, Changwat Songkhla, Thailand

Outcomes

Primary Outcomes

Incidence of PONV in ambulatory gynecologic laparoscopy

Time frame: four year

Data from ClinicalTrials.gov

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