The Effects of Dietary Factors on Physiological Subjective Stress Responses

University of Helsinki101 enrolled

Overview

The study aims to investigate the role of dietary factors in chronically stressed subjects. Previous studies have shown that milk proteins, B vitamins and probiotics may influence on subjective well-being in stressed subjects.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

101

Conditions

Chronic Stress

Interventions

Yogurt-like snacksDIETARY_SUPPLEMENT

twice a day 120 g for four weeks

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * STAI points 40-65 * BMI 18-30 kg/m2 * healthy Exclusion Criteria: * Gastrointestinal disease, diabetes or any other significant major medical morbidity * milk allergy * smoking * excess use of alcohol * pregnancy and breast feeding * waist circumference males \>102 cm, females \>88 cm * no medication or dietary supplements influencing measured responses

Locations (1)

University of Helsinki, Institute of Biomedicine

Helsinki, Finland

Outcomes

Primary Outcomes

Subjective well-being

Change in stress and mood states measured by State-trait anxiety inventory (STAI) and modified Profile of Mood States (POMS) at baseline and after 4 wk intervention

Time frame: baseline and 4 weeks

Secondary Outcomes

Physiological measurements

Change in salivary cortisol, blood pressure, heart beat variability, sleep and inflammatory markers.

Time frame: baseline and 4 weeks

Data from ClinicalTrials.gov

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