Office Hysteroscopy and Endometrial Snip Improve Intrauterine Insemination Outcome

Cairo University332 enrolled

Overview

Endometrial injury had been studied before prior to intracytoplasmic sperm injection (ICSI) cycles , in cases of repeated implantation failure. It is found that it will improve the implantation rate.

The investigators can combine office hysteroscopy to diagnose hidden endometrial pathology, with hysteroscopically guided endometrial snip from the fundus of the uterus, trying to improve the pregnancy rate.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

332

Conditions

Infertility

Interventions

Office hysteroscopy and endometrial snipPROCEDURE

Office hysteroscopy with endometrial snip

Office hysteroscopyPROCEDURE

Office hysteroscopy

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 38 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18- 38 years old * at least one patent tube * unexplained infertility, anovulation, mild to moderate male factor infertility * previous failed IUI Exclusion Criteria: * indicated for ICSI

Locations (1)

Kasr Al-AINY hospital

Cairo, Egypt

Outcomes

Primary Outcomes

Clinical pregnancy rate

Positive pregnancy test with fetal heart activity

Time frame: 10 month

Secondary Outcomes

Ongoing pregnancy rate

Pregnancy Continued after 12weeks

Time frame: 12 month

Data from ClinicalTrials.gov

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