5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori Infection

Inclusion Criteria: * H. pylori-infected patients who were at least 18 years of age and who had never received H. pylori eradication treatment were included in the study. Exclusion Criteria: * previous treatment for H. pylori infection, * use of inhibitors of acid secretion and/or antibiotics during the 6 weeks before the study, * gastrointestinal malignancy, * previous gastro-oesophageal surgery, * severe concomitant cardiovascular, * respiratory or endocrine diseases, * clinically significant renal or hepatic disease, * hematologic disorders, * any other clinically significant medical condition that could increase risk, * history of allergy to any of the drug used in the study, * pregnancy or lactation, * alcohol abuse, * drug addiction, * severe neurologic or psychiatric disorders, and * long-term use of corticosteroids or anti-inflammatory drugs.