A Human Trial to Assess the Low Density Lipoprotein Cholesterol (LDL-C) Lowering Effect of Soy

Inclusion Criteria: * Males and females (not pregnant or lactating) aged 30-70 year * Body mass index (BMI) ≤40kg/m² and ≥18.5kg/m² * Fasting plasma total cholesterol ≥5.0 * Fasting plasma LDL cholesterol ≥3.0 and \<5.0 mmol/L. Exclusion Criteria: * Fasting plasma triglycerides ≥4.0 mmol/L * Abnormal liver and kidney function * Unstable body weight(\>3kg change in 3 months) or intention to lose or gain weight; * Diabetes mellitus (fasting plasma glucose ≥7.0 mmol/L or use of insulin or any hypoglycemic or anti-hyperglycemic medication); * Use of any prescription or non-prescription drug, prebiotics or probiotics, herbal or nutritional supplement known to affect blood lipids, except for stable doses (no change in 3 months) of thyroxine, oral contraceptive agents, hormone replacement therapy, and medications for controlling blood pressure); * Major surgical or medical events within the past 3 months; * Presence of a gastrointestinal disorder or medication that alters the digestion and absorption of nutrients; including antibiotic use within the past 6 weeks. * Consumption of a diet containing ≥15% of energy from saturated fat; * Any food allergy or aversion or unwillingness to eat wheat, soy or milk; * Consumption of ≥5 servings per week of soy based food products; * Consumption of an average of \>2 alcoholic beverages per day; * Regular smokers (smoking ≥1 cigarette per day) of cigarettes or cigars