A Study of 25-hydroxy Vitamin d Levels in Non-itching Hemodialysis Patients

Winthrop University Hospital50 enrolled

Overview

Hypothesis: 25-hydroxy vitamin D levels in non-itching hemodialysis (HD) patients will be higher than those in HD patients with itching 25-hydroxy vitamin D levels will be measured in non-itching hemodialysis patients and compared to levels previously measured in a previous study of 25-hydroxy vitamin D levels of patients complaining of itching.

25-hydroxy vitamin D levels from non-itching HD patients in this study will be compared to 25-hydroxy vitamin D levels from our ongoing study in HD patients with itching. The primary endpoints for both studies are continuous variables. Student's t test will be used to test for statistical significance. Multiple regression analysis will be used for controlling covariates and testing the interaction among covariates.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Vitamin D Deficiency End Stage Renal Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Hemodialysis treatment for \> 3 months No complaints of itching within 1 month prior to study enrollment Exclusion Criteria: * Age \< 18 years * Failure to provide informed consent * Intact PTH \< 70 pg/ml or \> 1,000 pg/ml * Serum phosphorus \> 7.0 * Serum calcium (adjusted for albumin)\> 11 * Active malignancy * Likelihood of imminent renal transplantation * Current ergocalciferol treatment

Locations (2)

Winthrop University Hospital Dialysis Unit

Mineola, New York, United States

Winthrop University Hospital

Mineola, New York, United States

Outcomes

Primary Outcomes

25 hydroxy vitamin D level

Pt will have blood sample taken and fill out 1) Pruritis Survey 2) Phosphorus Restriction Compliance Survey

Time frame: up to 2 weeks

Data from ClinicalTrials.gov

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