Comparison of the Effects of Sevoflurane and Midazolam Used for the Maintenance of Anaesthesia on the Levels of Postoperative Cardiac Troponin I in Pediatric Cardiac Surgery

Baskent University50 enrolled

Overview

The purpose of this study is to compare two different anaesthetic agent effect on postoperative Troponin I levels in pediatric cardiac surgery

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Myocardial Injury Anaesthetic Preconditioning

Interventions

MidazolamDRUG

0.2 mg/kg/saat continuous infusion of midazolam received during anaesthesia

SevofluraneDRUG

end tidal concentration of % 0,5-8

Eligibility

Sex: ALLMin age: 1 MonthMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled for elective pediatric surgery * Patients written informed consent for study participation Exclusion Criteria: * Redo surgery * History of myocarditis * Renal failure * Pulmonary embolism * Hypothyroidism

Locations (1)

Baskent University, Faculty of Medicine

Ankara, Çankaya, Turkey (Türkiye)

Outcomes

Primary Outcomes

myocardial protective effect of sevoflurane

Postoperative troponin I levels

Time frame: postoperative 48 hours

Secondary Outcomes

Hemodynamic and respiratory data

Arterial pressure, heart rate, blood gas analysis, extubation time,

Time frame: Postoperative 48 hours

Data from ClinicalTrials.gov

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