Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)

Inclusion Criteria: * provide written informed consent prior to participation and be given a signed copy of the informed consent form; * be at least the age of legal consent; * be between 8 and 24 weeks of pregnancy; * have at least 20 natural teeth; * have moderate-to-severe gingivitis during pregnancy, including at least 30 intraoral sites with evidence of marginal gingival bleeding. Exclusion Criteria: * evidence of multiple gestations; * history of HIV infection, AIDS, autoimmune disease, or diabetes other than gestational diabetes; * indication for use of antibiotic pre-medication prior to dental procedures; * systemic corticosteroid or immunosuppressive therapy within 1 month of Baseline; * severe periodontal disease, rampant untreated dental caries, or other oral conditions that necessitate immediate dental care; * ongoing dental care that in the opinion of the investigator could impact study participation; * a history of allergies or hypersensitivity to mouth rinse products containing CPC; * any disease or condition that in the opinion of the investigator could interfere with the safe completion of the study; * randomization to a treatment in study 2011001 during a prior pregnancy.