The general objective of the study is to assess whether the implementation of the antibiotic essay with the Breakpoint/MIC ratio and data on penetration of the antibiotic in the site of infection may improve the outcome of infections compared to using only the standard procedures.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Prescription following in vitro sensitivity test implemented with MIC/Breakpoint ratio and penetration of antibiotic in the site of infection.
University of Naples Federico II
Naples, Naples, Italy
University of Naples Federico II
Naples, Italy
Complete recovery rate from infection
Complete resolution of fever, leukocytosis, and any local signs of infection
Time frame: At the end of treatment (an expected average of 10 days)
Time to recovery from infection.
Days to recovery completely from infection.
Time frame: At the end of treatment (an expected average of 10 days)
Partial response
Improvement of fever, leukocytosis, and any local signs of infection
Time frame: At the end of treatment (an expected average of 10 days)
Rate of non responders
Treatment failure, relapse and death. Failure is defined as no improvement or even worsening of the signs and symptoms of infection. Relapse is defined as the resumption of infection with the same organism at any body part within one month after completion of treatment
Time frame: At the end of treatment (an expected average of 10 days)
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