Studies of Pancreatic Islet Mass by Positron Emission Tomography (PET)

Uppsala University Hospital20 enrolled

Overview

This study investigates the hypothesis that differences in beta-cell mass in patients with diabetes and healthy individuals can be monitored by the positron emission tomography (PET) tracer \[11C\]5-hydroxytryptophane.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Type 1 Diabetes

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients with type 1 diabetes * Adult, healthy controls Exclusion Criteria: * Pregnancy * Impaired renal function

Locations (1)

Uppsala University Hospital

Uppsala, Sweden

Outcomes

Primary Outcomes

Difference in pancreatic uptake of % injected dose (ID) [11]5-hydroxy tryptophan between healthy volunteers and patients with long-standing type 1 diabetes

Time frame: To be measured at Positron emission tomography investigation for all study persons.

Data from ClinicalTrials.gov

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