The aim of this study is to see if paracetamol has a pain-relieving effect during eye examination in premature infants.
Retinopathy of prematurity (ROP) is a feared complication of premature birth. If discovered in time, the disease can be treated, and impaired vision or blindness can be reduced. Premature infants are therefore examined regularly after birth. However, the examination is painful and stressful for the infant. Painful experiences might lead to a pathological stress response later in life and should therefore be prevented. This is a double blinded, controlled and randomized study where the infants are examined and assessed either with or without the use of paracetamol.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
5
Paracetamol mixture 20 mg/kg + pacifier and glucose
pacifier and sucrose
St.Olavs University Hospital
Trondheim, Trøndelag, Norway
pain
Premature Infant Pain Profile (PIPP): score range 0-21. Used independently by 2 experienced observers
Time frame: 5 minutes
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