This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.
This study involves collecting and analyzing nasal mucus to see if there are changes in mucus properties during the course of a cold or episode of allergic rhinitis. Outcome measures include SNOT20 questionnaire, nasal secretion collection, acoustic rhinometry on the fifth and fourteenth day of symptoms. The investigators will also collect SNOT20 questionnaires on the tenth and twenty-eighth day.
Study Type
OBSERVATIONAL
Enrollment
41
Virginia Commonwealth University School of Medicine
Richmond, Virginia, United States
Nasal Secretion Collection
To measure the biophysical properties of nasal secretions for improved mucus clearance.
Time frame: 10 minutes
Subjective nasal scoring
The Sinus and Nasal Quality of Life Survey (SN-20) questionnaire assess the impact of infection on nasal symptoms, emotion, and activity on a scale of worsening symptoms scored 1 through 7 to provide a quantifiable score capable of comparing both disease severity and the impact of interventions on subjective complaints.
Time frame: 10 Minutes
Nasal Volume
Acoustic rhinometry is used to measure cross-sectional volume of the nasal cavity allowing the calculation of nasal volume.
Time frame: 15 Minutes
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