The Effects of Breakfast on Mental Workload

University of Helsinki13 enrolled

Overview

The aim of the study is to investigate the influence of nutritive (high-protein or high-carbohydrate) and non-nutritive (low energy) breakfast on psychological and physiological responses of mental workload during multitasking in healthy volunteers.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Healthy Subjects

Interventions

Breakfast juiceDIETARY_SUPPLEMENT

single dose (300 ml) in the morning of study day, 3 separate sessions (high-protein vs. high-carbohydrate vs. low-calorie juice), total duration 3 weeks

Eligibility

Sex: ALLMin age: 22 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * eats usually breakfast * use computer mouse with right hand * normal sleep-wake rhythm between 9 pm and 8 am * in females hormonal contraception Exclusion Criteria: * gastrointestinal disease, diabetes or any other significant major medical morbidity * milk allergy * lactose intolerance * smoking * excess use of alcohol, coffee, tea, cola drinks (\> 10 doses/day) * pregnancy and breast feeding * no medication or dietary supplements influencing measured responses * BMI \> 30 kg/m2 or \< 18 kg/m2

Locations (1)

University of Helsinki, Institute of Biomedicine

Helsinki, Finland

Outcomes

Primary Outcomes

Brain measures of mental workload (ERP 300 amplitude and latency) and heart rate

Time frame: 1 day

Secondary Outcomes

Subjective mental workload and mood measurement assessed using visual analogue scale in response to test meal.

Time frame: 1 day

cognitive function measurements

Time frame: 1 day

Blood concentration of glucose

Time frame: 1 day

salivary cortisol

Time frame: 1 day

Blood concentration of tryptophan in relation to other large neutral amino acids

Time frame: 1 day

Data from ClinicalTrials.gov

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