An Observational Study of Avastin in First Line in Elderly Patients With Metastatic Colorectal Cancer (CASSIOPEE)

Overall Survival

Overall survival was defined as the time between the treatment start date (date of the first infusion of bevacizumab) and date of all-cause death.

Time frame: From the time of first dose of study treatment to the time of death from any cause (Up to 53 months)

Percentage of Participants With Bevacizumab Administration

Time frame: Up to 36 months

Percentage of Participants With Adverse Events (AEs)

An AE was considered any unfavorable and unintended sign, symptom, or disease associated with the use of the study drug, whether or not considered related to the study drug.

Time frame: Up to 53 months

Percentage of Participants With Activities of Daily Living (ADL)

The Katz Activity of Daily Living (ADL) questionnaire scale contains 6 items evaluating in terms of autonomy or dependence the patient's ability to carry out basic activities of daily living (bathing, dressing, toileting, transfer, continence, feeding). Total score range 0 (low) to 6 (high). High score indicates participant is independent.

Time frame: Baseline, Month 6, 12, 24

Lawton Instrumental Activities of Daily Living Score (IADL)

The Lawton Instrumental Activities of Daily Living Scale (IADL) is an appropriate instrument to assess independent living skills. The instrument is most useful for identifying how a participant is functioning at the present time and for identifying improvement or deterioration over time. There are 8 domains of function measured with the Lawton IADL scale (telephone use, shopping, cooking, housekeeping, laundry, mode of transportation, responsibility of own medications, and ability to handle finances). Participants are scored according to their level of functioning from 0 (low function, dependent) to 8 (high function, independent). Higher score for each domain represents better functional performance of the older people.