The investigators will evaluate the National Institute of Health Stroke Scale/Score (NIHSS)in patients with stroke, and then give Minocycline 100mg po every 12 hours or placebo for five days, then perform periodic evaluations to determine the status and degree of neurological sequelae developed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
134
Minocicline 100mg oral twice a day for 5 days
Pills with vegetable fibers one pill oral twice a day for five days
University Hospital hernando Moncaleano Perdomo
Neiva, Huila Department, Colombia
RECRUITINGTo determine the efficacy of minocycline in reducing neurological sequelae in patients with stroke
The researchers evaluated the neurological condition of paralysis, aphasia,and level of consciousness by NIHSS score for each patient with stroke and proceeded to give minocycline or placebo. Then, the assessment was repeated after five and thirty days post treatment to determine whether their neurological sequelae had diminushed.
Time frame: one year
Identify the side effects of the intervention administered during the treatment time and 30 days later.
Time frame: one year
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