Changes of Endothelial Function Before and After DSA in Patients With Diabetes

Wuhan General Hospital of Guangzhou Military Command200 enrolled

Overview

Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Diabetes

Interventions

DSA assayOTHER

All patients with diabetic foot perform a DSA assay. Before and after DSA, endothelial function will be measured.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with diabetic foot * Age 40 to 70 years old Exclusion Criteria: * Heart failure * Renal failure * Acute infection

Locations (1)

Wuhan General Hospital

Wuhan, Hubei, China

Outcomes

Primary Outcomes

The changes of endothelial function

Time frame: 10 months

Data from ClinicalTrials.gov

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