Comparison Colon Capsule Endoscopy vs Optical Colonoscopy for Colorectal Cancer Screening in Familiar-Risk Population

Hospital Universitario de Canarias200 enrolled

Overview

The purpose of this study is to determine if the adherence to screening in first grade relatives of patients with CCR is higher than optical colonoscopy.

The purpose of this study is to compare the adherence and effectiveness of colon capsule endoscopy (CCE-2) versus conventional colonoscopy to screen first-degree relatives of patients with colorectal cancer.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

200

Conditions

Colorectal Cancer, Genetics of

Interventions

COLON CAPSULE ENDOSCOPY ADHERENCEPROCEDURE

An exploration with a COLON CAPSULE ENDOSCOPY eaten which capsule has a video-camera in both end to see the colon.

OPTICAL COLONOSCOPY ADHERENCEPROCEDURE

An exploration with an OPTICAL COLONOSCOPY from the anus to see the colon.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Asymptomatic first-degree relatives (parents, siblings or children) of CRC patients aged less than 60 years or with two or more first-degree relatives of any age. * Signing of informed consent. Exclusion Criteria: * Personal history of adenoma or CRC. * History of hereditary CRC. * Chronic inflammatory disease. * Presence of digestive symptoms. * Patients with swallowing problems (dysphagia). * Personal history of gastrointestinal surgery. * Enteritis radioactive. * Renal failure. * Congestive heart failure * Allergy or other contraindication to Bysacodyl to PEG or phosphates. * Pregnancy. * Suspected bowel obstruction or intestinal strictures or fistulas known. * Colectomy. * Paralysis with impaired intestinal motility. * Any other process that the investigator's discretion to make inadequate participation.

Locations (2)

Digestive Service, Huc

San Cristóbal de La Laguna, S/c de Tenerife, Spain

Hospital Universitario de Canarias

San Cristóbal de La Laguna, S/c de Tenerife, Spain

Outcomes

Primary Outcomes

Participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer

Assess whether colon capsule endoscopy increases participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer

Time frame: 6 month follow up

Data from ClinicalTrials.gov

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