The purpose of this study is to determine whether mechanical alternans (alternating strong and weak heart beats with a constant beat-to-beat interval), can be used to predict malignant ventricular arrhythmias, requiring defibrillation or appropriate ICD therapies, and to predict progression of heart failure and death.
Study Type
OBSERVATIONAL
Enrollment
134
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States
sudden arrhythmic death
appropriate ICD therapy due to fast ventricular tachycardia or ventricular fibrillation, or sudden cardiac death
Time frame: 5 years
cardiovascular mortality
Time frame: 5 years
all-cause death
Time frame: 5 years
appropriate ICD therapies
either ICD shock or antitachycardia pacing due to ventricular arrhythmia
Time frame: 5 years
composite heart failure endpoint
pump-failure death, or heart transplantation, or heart failure hospitalization, whichever came first
Time frame: 5 years
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