Comparison of Fractional Flow Reserve versus instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice * To compare FFR to iFR in arbitrary consecutive patients referred for percutaneous coronary intervention (PCI). * To investigate the influence of hyperemia on iFR. * To test reproducibility of iFR and FFR.
Study Type
OBSERVATIONAL
Enrollment
200
Stanford University
Stanford, California, United States
Cardiovascular Center Aalst
Aalst, Belgium
University Hospital Brno
Brno, Czechia
Catharina Ziekenhuis
Eindhoven, Netherlands
Stockholm South Hospital
Comparison of Fractional Flow Reserve vs. instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice
In this prospective, multicenter, international investigation, all consecutive patients in 5 centers, referred for PCI will be included. FFR will be submitted for one vessel in each patient - this will be the first vessel in which the FFR is performed. Measurements will be performed in duplicate. iFR will be calculated for all lesions for which an FFR measurement is submitted. In addition, iFR and FFR will be compared retrospectively in 1000 patients who had FFR measurements in the recent past
Time frame: 30 days
iFR at rest vs iFr during hyperemia
iFR is said to be independent of hyperemia. Accordingly a secondary outcome of this study will be a paired comparison of iFR at rest vs iFr with adenosine induced hyperemia.
Time frame: 30 days
Repeatability of iFr and FFR
To test repeatability of iFR and FFR
Time frame: 30 days
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Stockholm, Sweden