This is the first study focused on features/stereotypes of the first and second-line treatment patterns in Russia, comparison of different treatments, and determination of effective hormone treatment patterns in real-life practice with evaluation of pharmacoeconomic aspects. Study LINE is designed for collection of data on clinical effectiveness of second-line hormone treatment and quality of life in patients with breast cancer(BC).
LINE: Treatment patterns in postmenopausaL women wIth hormone receptor positive breast caNcEr
Study Type
OBSERVATIONAL
Enrollment
153
Research Site
Chita, Russia
Research Site
Irkutsk, Russia
Research Site
Kaluga, Russia
Collection of data of routine regimens of hormone therapy in postmenopausal women with hormone receptor-positive, locally advanced or metastatic breast cancer
Time frame: 2 years
Quality of life (QoL): the extent of reduction in QoL deficit from 1 visit
Time frame: 2 years
The extent of reduction anxiety inventory
Time frame: 2 years
Effectiveness: Tumor regression; number of patients with complete response (CR), partial response (PR) or stable disease
Time frame: 2 years
Historical data analysis: treatment patterns effectiveness, duration of the adjuvant or first-line hormone treatment
Time frame: 2 years
Response duration
Time frame: 2 years
Performance status (ECOG)
Time frame: 2 years
Co-morbidities and relevant historical data
Time frame: 2 years
The information on spontaneous office visit to oncologist or hospitalization including reasons, diagnosis, days of hospitalization, procedures and concomitant medication changes will be collected.
Time frame: 2 years
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Research Site
Kazan', Russia
Research Site
Kemerovo, Russia
Research Site
Khanty-Mansiysk, Russia
Research Site
Krasnodar, Russia
Research Site
Krasnoyarsk, Russia
Research Site
Moscow, Russia
Research Site
Omsk, Russia
...and 9 more locations