Combined Effects of Bioactive Compounds in Lipid Profile

Inclusion Criteria: * Adult patients \> 18 years old * LDL-c plasma levels ≥130 mg/dL and ≤ 189 mg/dL * Patients not requiring lipid-lowering drug treatment according to ATPIII guidelines,that do not have cardiovascular disease, stroke or intermittent claudication, diabetes mellitus, renal or Patients who have demonstrated effects or contraindications to lipid-lowering drug therapy (in this case, treatment should be discontinued 1 month before baseline. * Signed and dated informed consent before any study specific procedure. Exclusion Criteria: * Patients on drug therapy to reduce LDL-C, for example, statins, bile acid sequestrants, nicotinic acid, fibrates or similar (up to 1 month before baseline). * History of cardiovascular disease, stroke or intermittent claudication. * Diabetes mellitus (at least 2 blood fasting glucose greater than 126 mg / dL). * Having taken any functional food with sterols, stanols or similar or any nutraceutical with lipid-lowering effects during the previous 7 days. * Plasma levels of triglycerides \> 350 mg/dl * Diagnosis of familial hypercholesterolemia