Gender-specific aEEGs and Outcome in Preterms

Medical University of Vienna148 enrolled

Overview

Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography (aEEG) and to correlate these findings with neurodevelopmental outcome. Methods: Preterm infants born \<30 weeks' gestational age between 2000 and 2002 were prospectively included. aEEGs obtained within the first two weeks of life were evaluated and classified according to background activity, sleep-wake cycling (SWC) and seizure activity. Outcome was assessed at three years.

Study Type

OBSERVATIONAL

Enrollment

148

Conditions

Gender Role Disorder, Male to Female Type

Eligibility

Sex: ALLMin age: 24 WeeksMax age: 30 WeeksHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * born\<30 weeks gestational age * who had aEEGs in first 2 weeks of life * who were assessed for outcome at 3 years of age Exclusion Criteria: * born\>30 weeks gestational age * had no aEEGs in first 2 weeks of life * lost for follow-up at 3 years

Locations (1)

Medical University of Vienna

Vienna, Austria

Data from ClinicalTrials.gov

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