Change of Fructose to Fat in South Asians

Inclusion Criteria: * Males and females, 18-35 years of age. * South Asian or Caucasian descent through self-identification (South Asians are to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh and no known non-South Asian ancestry in parents; Caucasians are to have both biological parents who self-identify as Caucasian and no known non-Caucasian ancestry in parents). * Body mass index (BMI) 18.0-24.9 kg/m2 with no history of obesity. * Fasting glucose \<100 mg/dL, 2h glucose oral glucose tolerance test (OGTT) \< 140 mg/dL. * triglycerides (TG) \<200 mg/dL, HDL cholesterol (HDL-C) \>30 mg/dL, LDL cholesterol (LDL-C) \<160 mg/dL. * Willing and able to stop fish oil, fiber supplement, other non-prescribed vitamins/supplements for 1 week prior to visit #2 until completion of study. * Willing to not drink alcohol for 24-hours before visit #2. * Willing and able to provide informed consent. Exclusion Criteria: * History of diabetes or other endocrine disorder, hepatitis or other liver disorder, HIV, or autoimmune disease. * Medication(s) known to affect lipids, including hormonal contraceptives. * Recent acute illness * Gastrointestinal disease resulting in significant gastrointestinal dysfunction or malabsorption. * Cigarette smoking * History of ethanol abuse (current intake \>2 drinks/day) or illicit drugs. * History of severe psychiatric illness * If female, pregnant or breastfeeding * Participation in an investigational drug study within one month of screening. * Unusual diet or extreme level of physical activity * Have any other condition, which in the opinion of the investigator, should prohibit the participation in the study