EGD-assisted Bowel Preparation for Colonoscopy

Rockford Gastroenterology Associates82 enrolled

Overview

Adequate bowel preparation is of critical importance for colonoscopy. Particularly among hospitalized patients, inadequate bowel preparation for colonoscopy may arise due to patient intolerance to prescribed laxative regimen, elderly population, and co-existing conditions that impair the ability to ingest a large-volume laxative regimen. Improvements in bowel preparation for colonoscopy in hospitalized patients would likely improve patient care and reduce hospital costs. The purpose of this study is to determine if administering a portion of the bowel purgative via EGD could improve colonoscopy preparation in hospitalized patients.

In this randomized controlled trial in hospitalized patients, patients in whom colonoscopy was anticipated the day following EGD were consented and randomized to either standard prep by mouth (split-dose PEG) or intervention group (instillation of the first 2 liters of Nulytely solution through the channel of the endoscope into the duodenal bulb, then continue standard prep). Data is collected on quality of prep and patient satisfaction in both groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Esophagoscopy Techniques Colonoscopy

Interventions

EGD-assisted administration of colonoscopy prepPROCEDURE

Interventional group receive the first 2 liters of prep solution during EGD through the scope channel if colonoscopy expected the following day.

Control Group received standard prep by oral administrationPROCEDURE

Control group receive standard oral colonoscopy prep.

Outcomes

Primary Outcomes

Quality of bowel preparation

Quality of prep was assessed using the Ottawa bowel preparation scale (Rostom A, Jolicoeur E. Validation of a new scale for the assessment of bowel preparation quality. Gastrointest endosc 2004;59:482-6)

Time frame: Twenty four to 48 hours - from time of consent prior to EGD until end of colonoscopy performed the following day

Secondary Outcomes

Patient tolerance of bowel preparation

Patients in both groups were asked to indicate if the bowel prep was easy, slightly difficult, moderately difficult, extremely difficult, or if they were unable to complete the prep as directed.

Time frame: administered just prior to sedation for colonoscopy