Transdiagnostic Group Treatments for Patients With Common Mental Disorders in Primary Health Care

Karolinska Institutet245 enrolled

Overview

The purpose of this study is to compare the effects of CBT and MMI on the quality of life and relief of psychological symptoms of patients with common mental disorders or problems attending primary health care centre.

Design: Clinical randomised non blinded controlled trial. Setting: The study was performed in an outpatient primary health care centre serving 36 000 inhabitants. Participants: Patients (n=278), aged 18-65 years, with common mental problems or disorders were referred to the study by the GPs and 245 were included in the study. Interventions: Participants were randomised to CAU or one of two group interventions in addition to CAU. These were: a) group cognitive behavioural based therapy (CBT) administered by psychologists once a week for 12 weeks, and b) group multimodal intervention (MMI) based on a protocol comprising a mix of existing group interventions and exercises borrowed from multiple techniques and therapeutic schools and administered by assistant nurses with brief training, including two sessions per week for 6 weeks. Main outcome measures: Primary outcome measure was the Mental Component Summary score of SF-36. Secondary outcome measures were perceived stress scale (PSS) and Self-Rating Scale for Affective Syndromes (CPRS-S-A)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

245

Conditions

Anxiety Disorders Depressive Disorders Stress Disorders

Interventions

CBTBEHAVIORAL

group cognitive behavioural based therapy (CBT) administered by psychologists once a week for 12 weeks,

MMIBEHAVIORAL

group multimodal intervention (MMI) based on a protocol comprising a mix of existing group interventions and exercises borrowed from multiple techniques and therapeutic schools and administered by assistant nurses with brief training, including two sessions per week for 6 weeks.

CAUBEHAVIORAL

Care as usual by the GPs

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with common mental disorders or problems Exclusion Criteria: patients were excluded if: * they met diagnostic criteria for bipolar or psychotic disorder or severe personality disorder, * were judged to be at risk of committing suicidal acts, and * if they had undergone MMI earlier. The investigators paid no consideration to whether patients were treated with SSRI medication.

Locations (1)

Center for Family and Community Medicine, Karolinska Institutet,

Huddinge, Sweden

Outcomes

Primary Outcomes

Change in Quality of life as measured by the SF-36 (Mental Component Score)

Time frame: Change from baseline in SF-36 at 52 weeks

Secondary Outcomes

Change in Psychopathology as measured by the Comprehensive Psychopathological Rating Scale Self-asssessmen (CPRS-S-A)

Time frame: Change from baseline in CPRS-S-A at weeks 52

Data from ClinicalTrials.gov

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