Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)

Hormozgan University of Medical Sciences200 enrolled

Overview

This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs. Hypothesis: Normal saline or cefazolin irrigation decreases the incidence of SSIs.

All pregnant women who underwent cesarean after 6 hours passed their rupture of membrane and attended to Shariati Hospital of Bandarabbass were eligible for our study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

200

Conditions

Surgical Site Infections

Interventions

Cefazolin irrigationOTHER

after the surgery and before closing up the patients, 2 grams of cefazolin in 5 cc of distilled water was used to irrigate the patients

Normal Saline IrrigationOTHER

after the surgery and before closing up the patients, 150 cc of normal saline was used to irrigate the patients and in the last group

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * pregnant women * 6 hours passed their rupture of membrane * needed to undergo cesarean Exclusion Criteria: * allergy to penicillin * allergy to cefazolin * history of immunosuppressive drug use * gestational diabetes mellitus * preeclampsia

Locations (1)

Shariati Hospital

Bandar Abbas, Hormozgan, Iran

Outcomes

Primary Outcomes

SSI

Time frame: one week after discharge

Data from ClinicalTrials.gov

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