This study follows the results of the COMPALICLAMP study (NCT00951392) where the investigators showed a differential expression of sirtuins protein isoforms, Sirt6, in muscle depending on the quality of aging. The investigators seek to confirm this difference in expression level of circulating leukocytes on a larger sample.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
60
It is a single cross sectional study. All outcome measures will be taken during the investigation with physical examination, questionnaire and a blood sample
Centre de recherche en nutrition humaine Rhone-Alpes
Pierre-Bénite, France
Centre de Recherche en Nutrition Humaine
Pierre-Bénite, France
Sirt6 expression in circulating leukocytes based on the aging quality
analysis by quantitative RT-PCR method
Time frame: participants will be followed for the duration of the visit, an expected average of 1 day
hand and forearm muscular strength measurement
Hand Grip strength test
Time frame: participants will be followed for the duration of the visit, an expected average of 1 day
Physical examination and anthropometric measurement
Measurement of the weight, height, waist, hips, blood pressure, pulse.
Time frame: participants will be followed for the duration of the visit, an expected average of 1 day
Cognitive assessment
MMSE (Mini Mental State Examination), Five-word test, clock drawing
Time frame: participants will be followed for the duration of the visit, an expected average of 1 day
Physical Activity questionnaire
MAQ (Modifiable Activity Questionnaire)
Time frame: participants will be followed for the duration of the visit, an expected average of 1 day
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