Experience with Microbial Collagenase (trade name Xiapex) in Europe currently is limited to randomised controlled studies.While such studies are essential to determine efficacy and safety of the product (usually compared to placebo), they provide no information on the effectiveness of the drug and further aspects of its use (feasibility, tolerability, quality of life and other patient-related outcomes) in the typical "real-life" setting under clinical practice conditions.Thus, the present study aims to collect data on the * Drug utilization of Microbial Collagenase in the hand of physicians, with focus on feasibility, treatment patterns, and effectiveness in clinical practice * Context of Microbial Collagenase therapy (setting, patient characteristics, concomitant treatment, follow-up therapy) * Effectiveness (with focus on functionality) * Tolerability * Patient-related outcomes: patient satisfaction, health-related quality of life * Physician satisfaction with therapy * Resource utilization (hospital stays, drug consumption, concomitant medication etc.) * Long-term outcomes
Study Type
OBSERVATIONAL
Enrollment
87
Prof. Dr. Max Haerle
Markgröningen, Germany
Prof. Dr. Riccardo Giunta
Munich, Germany
Several undisclosed sites
Various Cities, Germany
Dr. Joerg Witthaut
Vogtareuth, Germany
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