Clinical and Genetic Factors Associated With Psychotic Symptoms Among Cocaine Abusers

Assistance Publique - Hôpitaux de Paris417 enrolled

Overview

The aim of this study is to determine the clinical, genetic and environmental factors associated with the phenotype "severe psychotic symptoms" caused by cocaine.

The second purpose is to include gene x environment interaction and to analyse the factors associated with the presence or the absence of severe psychotic symptoms induced by cocaine.

Study Type

OBSERVATIONAL

Enrollment

417

Conditions

Cocaine-induced Psychotic Disorder During Intoxication

Interventions

InterviewsOTHER

Interviews

Blood sampleOTHER

Blood sample

Hair sampleOTHER

Hair sample

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * Adults, cocaine users, who have signed an informed consent Exclusion criteria: * Poor venous condition (for blood samples), specially protected people, non French speaking, people who refuse to sign the consent.

Locations (1)

Espace Murger, Hôpital Fernand Widal

Paris, France

Outcomes

Primary Outcomes

causes and protective factors of Cocaine Induced Psychosis CIP

1. clinical data 2. biologic data 3. genetic data

Time frame: up to one day after taking cocaine

Secondary Outcomes

gene, environment interactions associated with CIP

clinical and genetic data

Time frame: up to one day after taking cocaine

Data from ClinicalTrials.gov

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