Stellate ganglion block (SGB) has been the alternative treatment of Meniere's disease for years. However, objective evidence of the effect of SGB was still lack. The investigators conducted a randomized controlled study to examine the immediate effects of SGB in SP/AP of electrocochleography (ECoG).
Ten patients were randomly assigned to receive stellate ganglion block. These ten patients made up the experimental group. Another ten patients in the control group were assigned to receiving one dosage of oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
stellate ganglion block
0.25mg of erispan@ (fludiazine), p.o. one dose only.
25mg cephadol@ (diphenidol) p.o. one dose only.
i Mei Medical Center Tainan, Taiwan, Taiwan
Tainan, Tainan, Taiwan
SP/AP of Electrocochleography
SP/AP of ECoG was recorded 2 hours after SGB. to be compared with the SP/AP of ECoG recorded before treatment
Time frame: ECoG was reorded 2 hours after SGB
SP/AP recorded at 4 hours after SGB
SP/AP recorded at 4 hours after SGB was compared with that of pretreatment with SGB
Time frame: 4 hours after SGB
SP/AP recorded at 6 hours after SGB
SP/AP recorded at 4 hours after SGB was compared with the SP/AP recorded before SGB
Time frame: 6 hours after SGB
scores of verbal scale for vertigo recorded at 6 hours after SGB
scores of verbal scale for vertigo recorded at 6 hours after SGB was compared to the scores recorded before SGB
Time frame: 6 hours after SGB
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200mg kentons@ (tocopherol nicotinate) p.o. one dose only.