Pilot Pharmacokinetic Study of New Nicotine Lozenge Formulations

Inclusion Criteria: * Healthy male subject aged 18 to 45 years (inclusive) * Current smoker of \< or = 10 cigarettes/day * Fagerström score \< or = 5 * Absence of any clinically significant abnormal finding at physical, ECG, biological examinations in the Investigator's opinion Exclusion Criteria: * Presence of any significant medical finding or significant history (in particular any cardio-vascular disease, severe renal or hepatic insufficiency, current gastric or duodenal ulcer or oesophagitis) that may impact the safety, the interpretation of the results and/or the participation of the subject in the study according to the opinion of the investigator * Current or recurrent buccal lesions