Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia

Inclusion Criteria: * Diagnosed with schizophrenia or schizoaffective disorder by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria * Reported smoking 10 or more cigarettes per day for at least the prior year * Expressed a desire to quit smoking and a willingness to set a smoking cessation date within 4 weeks of enrollment * Were psychiatrically stable on a fixed dose of an antipsychotic for the past 30 days or more * Reported no active substance use disorder other than nicotine or caffeine within 6 months of enrollment Exclusion Criteria: * Participants with neurologic risk factors for bupropion treatment were excluded from receiving bupropion but were eligible to participate and receive short- and long-acting NRT and CBT only.