Invasiveness and Chemoresistance of Cancer Stem Cells in Colon Cancer

Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * Patient with adenocarcinoma-type colorectal cancer: * stage III at diagnosis, surgical resection of the primary tumor proposed. * stage IV at diagnosis, surgical resection of the primary tumor and possibly of metastases proposed. * Stage IV who have already undergone surgical excision of the primary tumor, and for whom metastasectomy is now proposed. Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * Patients for whom surgical resection of the primary tumor is not considered as an option * PStage IV at diagnosis, but metastasectomy is not considered as an option * Patients with positive HIV, Hepatitis B or Hepatitis C serology