Combined Rg3-enriched Korean Red Ginseng and American Ginseng in the Management of Hypertension in Type 2 Diabetes

Inclusion Criteria: * between the age of 40 and 75 years * type 2 diabetes (at least 1 year duration, HbA1c ≥ 6.5%- ≤ 8.0%, treated with diet and/or oral hypoglycemic medications) * clinically diagnosed and treated hypertension according to Canadian Diabetes Association Clinical Practice Guidelines * normal thyroid, kidney and liver functions * female subjects recruited for the study must be post-menopausal or had absence of menstruation for ≥ 1 year or is taking contraceptive precautions Exclusion Criteria: * insulin therapy * history of angina, myocardial infarction or stroke * systolic blood pressure \>160 mmHg and/or diastolic blood pressure \>100 mmHg * use of ginseng within 1 month start of study * BMI \>35 kg/m2 * smoking cigarettes * alcohol intake of \> 2 drinks/day * recently given blood * have an upcoming planned surgery * GFR \<60 mL/min/1.73m2 * prolonged QT (\>20 ms) interval as assessed by ECG * changes to use of natural health products that may effect blood pressure and/or diabetes * weight change more than +/- 3 kg/month * HIV infection, inflammatory bowel disease, celiac disease, heart disease, bleeding disorder, sleep disorder, arrhythmia * pregnant or breastfeeding * use of anticoagulant (excluding aspirin), antiplatelet, sedative, sympathomimetic, photosensitizing or anti-depressant drugs * hormone replacement therapy, furosemide, morphine, glucocorticoids * presence of any conditions which, in the opinion of the Qualified Investigator, might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results * known sensitivity or allergy to any test product or placebo ingredients