Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia

Phase 4TerminatedNCT01579864

Hopital Foch6 enrolled

Overview

Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a rapid and complete reversal of the neuromuscular block. The aim of ths study is to compare both agents.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Anesthesia

Interventions

succinylcholineDRUG

Succinylcholine 1 mg/kg and a second dose if necessary. Rocuronium 0,4 mg/kg can be used as a rescue

rocuroniumDRUG

rocuronium 0,9 mg/kg with additional boluses of 0,3 mg/kg f necessary

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients scheduled for an interventional rigid bronchoscopy under general anesthesia Exclusion Criteria: * pregnant woman or woman of childbearing age, * morbid obesity, * drug allergy,contra-indication to succinylcholine, rocuronium, sugammadex, propofol, remifentanil, * history of central neurological or brain damage, * psychotropic treatment, * pacemaker, * renal failure, * disease of the neuromuscular junction.

Locations (1)

Hopital Foch

Suresnes, Île-de-France Region, France

Outcomes

Primary Outcomes

Score of quality of the surgical procedure

The quality of the surgical procedure is evaluated by the surgeon (composite score) who is unaware of the neuromuscular agent used (see Fuchs-Buder et al. Acta Anaesthesiol Scand 2007;51(7):789-808)

Time frame: one day

Secondary Outcomes

Score of quality of anesthesia

The quality of anesthesia is evaluated by the anesthesist in charge on a scale 0-30 (0-10 for the induction ; 0-10 for maintenance; 0-10 for recovery)

Time frame: one day

Data from ClinicalTrials.gov

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