The 64 pole basket catheter used for the mapping procedure will be defined "atypical" sites which sustain atrial fibrillation. The ablation through the driver will lead to more rapid ablation of the atrial fibrillation.
Atrial fibrillation (AF) is a common abnormal and rapid heart rhythm characterized by erratic electrical activity of the upper chambers of the heart. This cardiac arrhythmia may lead to stroke, heart failure, low blood pressure, chest pain, and increased mortality rate. Treatment may include medication to stop the rhythm abnormality, blood thinners, and/or ablation. Ablation involves application of heat or freezing to the area sustaining the rhythm abnormality. This requires tubes (catheters)to be placed in the heart. Human atrial fibrillation may be sustained by localized drivers (rapid and/or organized sites of atrial electrical activation). By mapping/recording the patient's specific atrial anatomy and atrial electrical activity with the 64-pole basket catheter, we may add to the knowledge base of these driver locations. We may also add to the knowledge about where best to ablate to terminate the arrhythmia. Typical anatomic
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
78
The 64 pole basket catheter expands into a small flexible balloon that conforms to the atrial anatomy.
Virginia Commonwealth University
Richmond, Virginia, United States
Percentage of Drivers in Right Atrial
To determine where atypical areas of drivers might be.
Time frame: 30 min
Time to Ablation of All Sources
total time taken to ablate all sources of rotors/focal sources in driver locations
Time frame: 30 minutes
Percentage of Patients With Greater Than One Right Atrial Source of Rotor/Focal Sources
percentage of patients
Time frame: 30 minutes
Average Number of Rotors/Focal Drivers in Diverse Locations
Time frame: 30 minutes
Number of Participants With Successful Use of 64 Pole Basket Catheter at Non-University of California San Diego Electrophysiology Labs
To determine if the 64 pole basket catheter will be successfully used to gather information on Atrial Fibrillation drivers.
Time frame: 30 min
Mean Time to Recurrence of Atrial Fibrillation
mean time to recurrence of atrial fibrillation
Time frame: 1 year
Single-procedure Freedom From Atrial Fibrillation
percentage of patients without prior ablation
Time frame: one year
Percentage of All Patients Who Underwent Ablation of Rotor/Focal Sources of Atrial Fibrillation
percentage of all patients who had ablation perfornmed
Time frame: 1 year
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