The Effect of Endurance Training in Patients With Prostate Cancer

Inge Holm30 enrolled

Overview

The aim of the present study is to investigate the effect of endurance on PSA doubling time in prostate cancer patients with an elevation in PSA following radical prostatectomy for localized cancer. Furthermore, underlying mechanisms such as reduction in inflammatory markers and improvement in insulin sensitivity and body composition are investigated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Prostate Cancer Insulin Sensitivity Body Composition, Beneficial

Interventions

endurance trainingBEHAVIORAL

2 years of home-based endurance training

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Prostate cancer patients with an increase in PSA following radical prostatectomy Exclusion Criteria: * severe cardiovascular disease * severe arthritis * severe neuropathy * severe hypertension * therapy with antidiabetic agents * other treatment for prostate cancer than radical prostatectomy

Locations (1)

Centre of Inflammation and Metabolism, Rigshospitalet

Copenhagen, Copenhagen, Denmark

Outcomes

Primary Outcomes

PSA doubling time

Time frame: 2 years

Secondary Outcomes

Insulin sensitivity, body composition and inflammation status

Time frame: 0 months, 6 months and 24 months of training

Data from ClinicalTrials.gov

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