The effect of administration of vitamin D is tested on the long-term control of blood sugar (as measured by HbA1-c levels in blood) and mean blood pressure (as measured by 24 hour blood pressure profiles)in patients with stable type 2 diabetes mellitus
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
51
300 000 U intramuscularly, one dosage, in subjects with 25 (OH) vit D levels below 80 nmol/L, another dosage of 150 000 U after 3 months if 25(OH)vit D levels continue to be below 80 nmol/L.
1 ml of 0.9 % of NaCl at the beginning and 0.5 ml of 0.9 % NaCl after three months
Department of medicine, Kantonsspital Bruderholz
Bruderholz/Basel, Basel-Landschaft, Switzerland
Change in HBA1-c levels
Time frame: 3 and 6 months
24 hour mean blood pressure
Time frame: 3 and 6 months
plasma glucose
Time frame: 3 and 6 months
HOMA
Time frame: 6 months
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