Reperfusion With Cooling in Cerebral Acute Ischemia

Inclusion Criteria: * Age 18-85 years old * Symptoms consistent with an ischemic stroke with a large vessel occlusion (MCA, ICA-terminus) as determined by vascular imaging * ASPECTS score of 5-7 on non-contrast CT of the brain * Ability to undergo endovascular reperfusion therapy * Must have no contraindications to general anesthesia * A pre-treatment modified Rankin Score of 0 or 1 * Arterial puncture performed under 8 hours from symptom onset or last seen normal * Immediate post reperfusion CT scan shows no hemorrhage Exclusion Criteria: * Bleeding diathesis with a platelet count \< 50,000 or INR \> 1.5 * Involved in another clinical trial * History of dementia * End stage renal disease on hemodialysis * History of ventricular dysrhythmias * Life threatening medical condition precluding survival under 6 months * Presence of an IVC filter * Contrast dye allergy with history of anaphylaxis