Drug Interaction Study of SAR302503 in Patients With Solid Tumor

Inclusion criteria : * Histologically or cytologically confirmed advanced solid malignancy that is metastatic or unresectable, and for which standard curative measures do not exist * Signed informed consent Exclusion criteria: * Less than 18 years of age. * Limited physical functioning (as evaluated by the Eastern Cooperative Oncology Group (ECOG) scale) * Inability to follow study requirements and schedule * Treatment of cancer within 3 weeks of study, concurrent treatment in another clinical trial or with any other anti-cancer therapy * Serious medical illness at same time of study and/or significantly abnormal lab reports * Lack of pregnancy contraception (women of childbearing potential), pregnancy, or breast feeding. * Men who partner with a woman of childbearing potential, unless they agree to use effective contraception while on study drug * Continued toxic effects of prior chemotherapy * Evidence of other concurrent active malignancy * Other concurrent serious illness or medical condition * Cardiac abnormalities include bradycardia, AV block or other conduction defect on ECG, and patients taking a beta blocker. * Patients with Insulin-Dependent Diabetes Mellitus. * Patients with known active (acute or chronic) hepatitis A, B, C, and hepatitis B and C carries. Prior history of chronic liver disease (e.g., chronic alcoholic liver disease, autoimmune hepatitis, sclerosing cholangitis, primary biliary cirrhosis, hemachromatosis, non-alcoholic steatohepatitis \[NASH\]). * Inadequate organ function * History of partial or total gastrectomy, or, if in the opinion of the investigator, have any other disorder that would inhibit absorption of oral medications. The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.