Laryngeal Injuries After Anesthesia Induction With Sevoflurane and After Anesthesia Induction With Rocuronium

University of Rostock60 enrolled

Overview

Anesthesia induction with sevoflurane is not associated with an increased incidence or severity of laryngeal injuries compared with an anesthesia induction with a muscle relaxant.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Laryngeal Injuries

Interventions

SevofluraneDRUG

anesthesia induction with propofol, remifentanil and sevoflurane; afterwards tracheal intubation

RocuroniumDRUG

anesthesia induction with propofol, remifentanil and rocuronium; afterwards tracheal intubation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ear-nose-throat surgery * orotracheal intubation for surgery of the ear Exclusion Criteria: * obesity * allergy against the study drugs * patients with a known or suspected difficult airway (Mallampati score 3 or 4 and a mouth opening \< 3.5 cm). * all patients were examined by stroboscopy one day before surgery and were excluded from the study when preexisting pathologies of the vocal cords were found

Locations (1)

University of Rostock

Rostock, Mecklenburg-Vorpommern, Germany

Outcomes

Primary Outcomes

incidence of vocal cord injuries

Time frame: 24 h after tracheal intubation

Secondary Outcomes

incidence of hoarseness

Time frame: 24h, 48 h, and 72 h after tracheal intubation

incidence of soar throat

Time frame: 24h, 48h, and 72 h after tracheal intubation

Data from ClinicalTrials.gov

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