Hyperlipidemia and Statin Therapy in Amyotrophic Lateral Sclerosis

Inclusion Criteria: * A clinical diagnosis of laboratory-supported probable, probable, or definite familial, sporadic ALS, according to a modified El Escorial criteria (ref), by the study investigators * Time from disease onset is less than three years * 18 years of age * Subjects with diagnosis of hyperlipidemia and/or taking lipid lowering medications will not be excluded from study. Exclusion Criteria: * Requirement for tracheotomy ventilation or non-invasive ventilation for \> 23 hours per day * Diagnosis of other neurodegenerative diseases (Parkinson disease, Alzheimer disease, etc) * A clinically significant history of significant medical illness (advanced cancer, chronic inflammatory/infectious conditions, etc) within six months of baseline * Use of progestins, anabolic steroids, and corticosteroids within 45 days of baseline visit. Therapy is allowed as medically indicated after baseline visit.